Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:ZRANB2Official Gene Full Name:Zinc finger, RAN-binding domain containing 2NCBI Gene Id:9406Protein Name:Zinc finger Ran-binding domain-containing protein 2Swissprot Id:Q5VV34Protein Accession #:NP_976225Nucleotide Accession #:NM_203350Alias Symbols:ZIS, ZIS1, ZIS2, ZNF265Replacement Item:This antibody may replace item sc-102198 from Santa Cruz Biotechnology.Description of Target:ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-70K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >100 uncharacterized proteins in the sequence data bases that contain this domain.Protein Size (# AA):330Molecular Weight:37kDaPurification:Protein A purifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express ZNF265. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express ZNF265. 
Immunogen:The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF265Predicted Homology Based on Immunogen Sequence:Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%Complete computational species homology data:Anti-ZNF265 (ARP37747_T100)Peptide Sequence:Synthetic peptide located within the following region: RCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:UBC; C18orf25; TBC1D17; CORO1B; PARVA; SWAP70; OSBP; CDK1; FBXL7; SRPK2; SRPK1; CSNK2A1; KIF20A; SMURF1; UBE2B; UBA52; TYMS; TTC1; SULT1A1; SRSF7; PSMA1; PCMT1; UCHL3; UBE2V2; TTC9C; SRXN1; UNK; UBL7; ZNF644; UBQLN1; UBQLN2; UBXN7; TTLL12; UBE2C; AHCYL1; Blocking Peptide:For anti-ZRANB2 (ARP37747_T100) antibody is Catalog # AAP37747 (Previous Catalog # AAPP08829)Datasheets/Manuals:Printable datasheet for anti-ZRANB2 (ARP37747_T100) antibody
