| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Replacement Item | This antibody may replace item sc-177183 from Santa Cruz Biotechnology. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86% |
| Complete computational species homology data | Anti-SCNN1B (ARP34936_P050) |
| Peptide Sequence | Synthetic peptide located within the following region: QPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI |
| Concentration | Batch dependent within range: 100 ul at 0.5 - 1 mg/ml |
| Blocking Peptide | For anti-SCNN1B (ARP34936_P050) antibody is Catalog # AAP34936 (Previous Catalog # AAPP06159) |
| Datasheets/Manuals | Printable datasheet for anti-SCNN1B (ARP34936_P050) antibody |
| Subunit | beta |
| Target Reference | Snyder,P.M., et al., (2004) J. Biol. Chem. 279 (44), 45753-45758 |
| Gene Symbol | SCNN1B |
|---|---|
| Official Gene Full Name | Sodium channel, non-voltage-gated 1, beta subunit |
| Alias Symbols | BESC1, ENaCb, SCNEB, ENaCbeta |
| NCBI Gene Id | 6338 |
| Protein Name | Amiloride-sensitive sodium channel subunit beta |
| Description of Target | When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension. |
| Swissprot Id | P51168 |
| Protein Accession # | NP_000327 |
| Nucleotide Accession # | NM_000336 |
| Protein Size (# AA) | 640 |
| Molecular Weight | 70kDa |
| Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express SCNN1B.  |
| RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express SCNN1B.  |
| Protein Interactions | NEDD4L; SERP1; SCNN1G; SCNN1A; COMMD1; UBC; USP2; RAF1; NEDD4; TSC22D3; SGK1; EPN1; AP1M2; NFASC; CNTN1; WWP2; SCNN1D; ANK3; STX1A; ITCH; HECW1; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
- IHC Tips & Tricks
- ICC Tips & Tricks
- ELISA Tips & Tricks
- WB/IB Tips & Tricks
- IP Tips & Tricks
See our General FAQ page.
- Reviewed Data:
- Product Protocols: SCNN1B antibody tested with Human Jurkat Cells (ARP34936_P050)
- Technical Question: What is the stability/shelf-life of the SCCN1B antibody if A. stored lyophilized at -20 degrees, B. if diluted to 50 ul distilled water according to data sheet instructions?
What is the species homology for "SCNN1B Antibody - C-terminal region (ARP34936_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat".
How long will it take to receive "SCNN1B Antibody - C-terminal region (ARP34936_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
What buffer format is "SCNN1B Antibody - C-terminal region (ARP34936_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "SCNN1B Antibody - C-terminal region (ARP34936_P050)"?
This target may also be called "BESC1, ENaCb, SCNEB, ENaCbeta" in publications.
What is the shipping cost for "SCNN1B Antibody - C-terminal region (ARP34936_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "SCNN1B Antibody - C-terminal region (ARP34936_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "SCNN1B Antibody - C-terminal region (ARP34936_P050)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "70kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "SCNN1B Antibody - C-terminal region (ARP34936_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "SCNN1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "SCNN1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "SCNN1B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "SCNN1B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "SCNN1B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "SCNN1B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
