| Tested Species Reactivity | Human, Mouse, Rat |
|---|---|
| Predicted Species Reactivity | Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB, IF |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Replacement Item | This antibody may replace item sc-127974 from Santa Cruz Biotechnology. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human TRPA1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 90%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 100% |
| Complete computational species homology data | Anti-TRPA1 (ARP35205_P050) |
| Peptide Sequence | Synthetic peptide located within the following region: KCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLAL |
| Concentration | Batch dependent within range: 100 ul at 0.5 - 1 mg/ml |
| Blocking Peptide | For anti-TRPA1 (ARP35205_P050) antibody is Catalog # AAP35205 (Previous Catalog # AAPP23891) |
| Datasheets/Manuals | Printable datasheet for anti-TRPA1 (ARP35205_P050) antibody |
| Target Reference | Chen,J., (2008) J. Neurosci. 28 (19), 5063-5071 |
| Publications | Kun, J; Perkecz, A; Knie, L; Sétáló, G; Tornóczki, T; Pintér, E; Bán, Ã; TRPA1 receptor is upregulated in human oral lichen planus. 23, 189-198 (2017). IHC, WB, IF, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast 27718297 Pierce, A. N., Ryals, J. M., Wang, R. & Christianson, J. A. Vaginal hypersensitivity and hypothalamic-pituitary-adrenal axis dysfunction as a result of neonatal maternal separation in female mice. Neuroscience 263, 216-30 (2014). IHC, WB, IF, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast 24462609 Rohn, T. T., Catlin, L. W., Coonse, K. G. & Habig, J. W. Identification of an amino-terminal fragment of apolipoprotein E4 that localizes to neurofibrillary tangles of the Alzheimer’s disease brain. Brain Res. 1475, 106-15 (2012). IHC, WB, IF, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast 22905134 Trevisan, G; Benemei, S; Materazzi, S; De Logu, F; De Siena, G; Fusi, C; Fortes Rossato, M; Coppi, E; Marone, IM; Ferreira, J; Geppetti, P; Nassini, R; TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress. 139, 1361-77 (2016). IHC, WB, IF, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast 26984186 |
| Gene Symbol | TRPA1 |
|---|---|
| Official Gene Full Name | Transient receptor potential cation channel, subfamily A, member 1 |
| Alias Symbols | ANKTM1 |
| NCBI Gene Id | 8989 |
| Protein Name | Transient receptor potential cation channel subfamily A member 1 |
| Description of Target | The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in sig |
| Swissprot Id | O75762 |
| Protein Accession # | NP_015628 |
| Nucleotide Accession # | NM_007332 |
| Protein Size (# AA) | 1119 |
| Molecular Weight | 127kDa |
| Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express TRPA1.  |
| RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express TRPA1.  |
| Protein Interactions | UBC; CYLD; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
- IHC Tips & Tricks
- ICC Tips & Tricks
- ELISA Tips & Tricks
- WB/IB Tips & Tricks
- IP Tips & Tricks
See our General FAQ page.
- Reviewed Data:
- Customer Reviews for TRPA1 Antibody (ARP35205_P050) tested with rat sensory ganglia in Immunohistochemistry
- Product Protocols: TRPA1 antibody tested with Human Fetal Stomach Tissue (ARP35205_P050)
- Product Review: TRPA1 antibody - middle region (ARP35205_P050) in Rat sensory ganglia using Immunohistochemistry (IHC)
What is the species homology for "TRPA1 Antibody - middle region (ARP35205_P050)"?
The tested species reactivity for this item is "Human, Mouse, Rat". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast".
How long will it take to receive "TRPA1 Antibody - middle region (ARP35205_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
What buffer format is "TRPA1 Antibody - middle region (ARP35205_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "TRPA1 Antibody - middle region (ARP35205_P050)"?
This target may also be called "ANKTM1" in publications.
What is the shipping cost for "TRPA1 Antibody - middle region (ARP35205_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "TRPA1 Antibody - middle region (ARP35205_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "TRPA1 Antibody - middle region (ARP35205_P050)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "127kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "TRPA1 Antibody - middle region (ARP35205_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "TRPA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "TRPA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "TRPA1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "TRPA1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "TRPA1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "TRPA1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
