| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human SNRP70 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100% |
| Complete computational species homology data | Anti-SNRP70 (ARP40439_P050) |
| Peptide Sequence | Synthetic peptide located within the following region: RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDR |
| Concentration | Batch dependent within range: 100 ul at 0.5 - 1 mg/ml |
| Blocking Peptide | For anti-SNRNP70 (ARP40439_P050) antibody is Catalog # AAP40439 (Previous Catalog # AAPP22180) |
| Datasheets/Manuals | Printable datasheet for anti-SNRNP70 (ARP40439_P050) antibody |
| Sample Type Confirmation | SNRNP70 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Target Reference | Brandenberger,R., (2004) Nat. Biotechnol. 22 (6), 707-716 |
| Publications | Franklin, S. et al. Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Mol. Cell. Proteomics 11, M111.014258 (2012). IHC, WB, Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat 22270000 Franklin, S. et al. Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy. Mol. Cell. Proteomics 10, M110.000703 (2011). IHC, WB, Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat 20807835 Serini, S. et al. DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and b-catenin nuclear translocation. Carcinogenesis 33, 164-73 (2012). IHC, WB, Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat 22045024 |
| Gene Symbol | SNRNP70 |
|---|---|
| Official Gene Full Name | Small nuclear ribonucleoprotein 70kDa (U1) |
| Alias Symbols | RNPU1Z, RPU1, U170K, U1AP, U1RNP, Snp1, SNRP70, U1-70K |
| NCBI Gene Id | 6625 |
| Protein Name | U1 small nuclear ribonucleoprotein 70 kDa |
| Description of Target | SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. |
| Swissprot Id | P08621 |
| Protein Accession # | NP_003080 |
| Nucleotide Accession # | NM_003089 |
| Protein Size (# AA) | 437 |
| Molecular Weight | 51kDa |
| Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express SNRP70.  |
| RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express SNRP70.  |
| Protein Interactions | IL32; UBC; NEDD8; LIN28A; EZH2; SUZ12; EED; RNF2; rev; WBP4; SRPK2; SRPK1; MYC; SRPK3; HDAC2; PAN2; SMURF2; PRPF40A; CDKL3; RNF11; PRKD2; SKIL; RELA; RASGRF1; SMAD9; SMAD5; SMAD4; SMAD3; SMAD2; CHERP; PRMT5; UBL4A; VCAM1; SMAD1; ITGA4; IL7R; IFIT3; IFIT1; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
- IHC Tips & Tricks
- ICC Tips & Tricks
- ELISA Tips & Tricks
- WB/IB Tips & Tricks
- IP Tips & Tricks
See our General FAQ page.
- Reviewed Data:
- Product Protocols: SNRP70 antibody tested with Human Hepg2 Cells (ARP40439_P050)
- Product Protocol: Rabbit Anti-SNRNP70 Antibody (ARP40439_P050) in Human Pineal Tissue using Immunohistochemistry
- Product Protocol: Rabbit Anti-SNRNP70 Antibody (ARP40439_P050) in Human Pineal Tissue using Immunohistochemistry
- Product Protocols: SNRP70 antibody tested with HEK293Cells (ARP40439_P050)
- Product Protocols: SNRP70 antibody tested with Human RajiCells (ARP40439_P050)
What is the species homology for "SNRP70 Antibody - C-terminal region (ARP40439_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat".
How long will it take to receive "SNRP70 Antibody - C-terminal region (ARP40439_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
What buffer format is "SNRP70 Antibody - C-terminal region (ARP40439_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "SNRP70 Antibody - C-terminal region (ARP40439_P050)"?
This target may also be called "RNPU1Z, RPU1, U170K, U1AP, U1RNP, Snp1, SNRP70, U1-70K" in publications.
What is the shipping cost for "SNRP70 Antibody - C-terminal region (ARP40439_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "SNRP70 Antibody - C-terminal region (ARP40439_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "SNRP70 Antibody - C-terminal region (ARP40439_P050)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "51kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "SNRP70 Antibody - C-terminal region (ARP40439_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "SNRNP70"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "SNRNP70"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "SNRNP70"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "SNRNP70"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "SNRNP70"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "SNRNP70"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
