| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Human |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human GTF2H1 |
| Purification | Affinity purified |
| Peptide Sequence | Synthetic peptide located within the following region: LGKNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIINSFQSIRQEME |
| Concentration | Batch dependent within range: 100 ul at 0.5 - 1 mg/ml |
| Blocking Peptide | For anti-GTF2H1 (ARP97725_P050) antibody is Catalog # AAP97725 |
| Datasheets/Manuals | Printable datasheet for anti-GTF2H1 (ARP97725_P050) antibody |
| Gene Symbol | GTF2H1 |
|---|---|
| Official Gene Full Name | general transcription factor IIH subunit 1 |
| Alias Symbols | P62, BTF2, TFB1, TFIIH |
| NCBI Gene Id | 2965 |
| Protein Name | P62, BTF2, TFB1, TFIIH |
| Description of Target | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. |
| Swissprot Id | P32780 |
| Protein Accession # | NP_001135779.1 |
| Nucleotide Accession # | NM_001142307.1 |
| Protein Size (# AA) | 548 |
| Molecular Weight | 60 kDa |
| Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express GTF2H1.  |
| RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express GTF2H1.  |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
- IHC Tips & Tricks
- ICC Tips & Tricks
- ELISA Tips & Tricks
- WB/IB Tips & Tricks
- IP Tips & Tricks
See our General FAQ page.
What is the species homology for "GTF2H1 Antibody - middle region (ARP97725_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".
How long will it take to receive "GTF2H1 Antibody - middle region (ARP97725_P050)"?
This item is available "Domestic: within 24 hours delivery | International: 3-5 days".
What buffer format is "GTF2H1 Antibody - middle region (ARP97725_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "GTF2H1 Antibody - middle region (ARP97725_P050)"?
This target may also be called "P62, BTF2, TFB1, TFIIH" in publications.
What is the shipping cost for "GTF2H1 Antibody - middle region (ARP97725_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "GTF2H1 Antibody - middle region (ARP97725_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "GTF2H1 Antibody - middle region (ARP97725_P050)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "60 kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "GTF2H1 Antibody - middle region (ARP97725_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "GTF2H1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "GTF2H1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "GTF2H1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "GTF2H1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "GTF2H1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "GTF2H1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
