| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | WB, IHC, IF |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Replacement Item | This antibody may replace item HPA027305 |
| Immunogen | A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser927 of human NFKB1 |
| Purification | Affinity purified against immunogen |
| Datasheets/Manuals | Printable datasheet for anti-NFKB1 (OAAN02904) |
| Preservative | 0.02% Sodium Azide |
| Target Post-Translational Modification | Phospho-Ser927 |
| Application Info | WB: 1:500 - 1:2,000. IHC: 1:50 - 1:100. IF: 1:100 - 1:200 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Gene Symbol | NFKB1 |
|---|---|
| Official Gene Full Name | nuclear factor kappa B subunit 1 |
| Alias Symbols | p50, KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B, p50, KBF1, p105, EBP-1, CVID12, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B, nuclear factor kappa B subunit 1, Nuclear factor NF-kappa-B p105 subunit, N |
| NCBI Gene Id | 4790 |
| Protein Name | Nuclear factor NF-kappa-B p105 subunit |
| Description of Target | This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. |
| Swissprot Id | P19838 |
| Protein Accession # | NP_001158884.1 |
| Nucleotide Accession # | NM_001165412.1 |
| Molecular Weight | 120 kDa |
| Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express NFKB1.  |
| RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express NFKB1.  |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
- IHC Tips & Tricks
- ICC Tips & Tricks
- ELISA Tips & Tricks
- WB/IB Tips & Tricks
- IP Tips & Tricks
See our General FAQ page.
What is the species homology for "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
How long will it take to receive "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
What buffer format is "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)" provided in?
This item is provided in "Liquid".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)"?
This target may also be called "p50, KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B, p50, KBF1, p105, EBP-1, CVID12, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B, nuclear factor kappa B subunit 1, Nuclear factor NF-kappa-B p105 subunit, N" in publications.
What is the shipping cost for "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "120 kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "NFKB1 Antibody (Phospho-Ser927) (OAAN02904)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "NFKB1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "NFKB1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "NFKB1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "NFKB1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "NFKB1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "NFKB1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
