| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | WB, IF |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser166 of human MDM2 |
| Purification | Affinity purified against immunogen |
| Datasheets/Manuals | Printable datasheet for anti-MDM2 (OAAN02751) |
| Preservative | 0.02% Sodium Azide |
| Target Post-Translational Modification | Phospho-Ser166 |
| Application Info | WB: 1:500 - 1:1,000. IF: 1:50 - 1:100 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Gene Symbol | MDM2 |
|---|---|
| Official Gene Full Name | MDM2 proto-oncogene |
| Alias Symbols | HDMX, hdm2, ACTFS, HDMX, hdm2, ACTFS, MDM2 proto-oncogene, E3 ubiquitin-protein ligase Mdm2, MDM2 |
| NCBI Gene Id | 4193 |
| Protein Name | E3 ubiquitin-protein ligase Mdm2 |
| Description of Target | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |
| Swissprot Id | Q00987 |
| Protein Accession # | NP_001138811.1 |
| Nucleotide Accession # | NM_001145339.2 |
| Molecular Weight | 55 kDa |
| Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express MDM2.  |
| RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express MDM2.  |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
- IHC Tips & Tricks
- ICC Tips & Tricks
- ELISA Tips & Tricks
- WB/IB Tips & Tricks
- IP Tips & Tricks
See our General FAQ page.
What is the species homology for "MDM2 Antibody (Phospho-Ser166) (OAAN02751)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
How long will it take to receive "MDM2 Antibody (Phospho-Ser166) (OAAN02751)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
What buffer format is "MDM2 Antibody (Phospho-Ser166) (OAAN02751)" provided in?
This item is provided in "Liquid".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "MDM2 Antibody (Phospho-Ser166) (OAAN02751)"?
This target may also be called "HDMX, hdm2, ACTFS, HDMX, hdm2, ACTFS, MDM2 proto-oncogene, E3 ubiquitin-protein ligase Mdm2, MDM2" in publications.
What is the shipping cost for "MDM2 Antibody (Phospho-Ser166) (OAAN02751)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "MDM2 Antibody (Phospho-Ser166) (OAAN02751)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "MDM2 Antibody (Phospho-Ser166) (OAAN02751)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "55 kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "MDM2 Antibody (Phospho-Ser166) (OAAN02751)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "MDM2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "MDM2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "MDM2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "MDM2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "MDM2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "MDM2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
