| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | WB, IF |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Tyr753 of human PLCG2 |
| Purification | Affinity purified against immunogen |
| Datasheets/Manuals | Printable datasheet for anti-PLCG2 (OAAN02835) |
| Preservative | 0.02% Sodium Azide |
| Target Post-Translational Modification | Phospho-Tyr753 |
| Application Info | WB: 1:500 - 1:2,000. IF: 1:100 - 1:200 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Gene Symbol | PLCG2 |
|---|---|
| Official Gene Full Name | phospholipase C gamma 2 |
| Alias Symbols | FCAS3, APLAID, RP11-510J16.3, FCAS3, APLAID, PLC-IV, PLC-gamma-2, phospholipase C gamma 2, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, PLCG2 |
| NCBI Gene Id | 5336 |
| Protein Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 |
| Description of Target | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. |
| Swissprot Id | P16885 |
| Protein Accession # | NP_002652.2 |
| Nucleotide Accession # | NM_002661.4 |
| Molecular Weight | 150 kDa |
| Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express PLCG2.  |
| RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express PLCG2.  |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
- IHC Tips & Tricks
- ICC Tips & Tricks
- ELISA Tips & Tricks
- WB/IB Tips & Tricks
- IP Tips & Tricks
See our General FAQ page.
What is the species homology for "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
How long will it take to receive "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
What buffer format is "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)" provided in?
This item is provided in "Liquid".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)"?
This target may also be called "FCAS3, APLAID, RP11-510J16.3, FCAS3, APLAID, PLC-IV, PLC-gamma-2, phospholipase C gamma 2, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, PLCG2" in publications.
What is the shipping cost for "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "150 kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "PLCG2 Antibody (Phospho-Tyr753) (OAAN02835)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "PLCG2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "PLCG2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "PLCG2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "PLCG2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "PLCG2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "PLCG2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
