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当前位置: 首页 > 产品中心 > Anti_Human > avivasysbio/Human CHEK1 Antibody : PE (Phospho-Ser345) (OAAQ00113)/OAAQ00113
商品详细avivasysbio/Human CHEK1 Antibody : PE (Phospho-Ser345) (OAAQ00113)/OAAQ00113
avivasysbio/Human CHEK1 Antibody : PE (Phospho-Ser345) (OAAQ00113)/OAAQ00113
avivasysbio/Human CHEK1 Antibody : PE (Phospho-Ser345) (OAAQ00113)/OAAQ00113
商品编号: OAAQ00113
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 抗人
公司分类: Anti_Human
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Tested Species Reactivity:
Human, Mouse, Rat
Predicted Species Reactivity:
Mouse, Rat
Product Format:
Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.
Clonality:
Monoclonal
Clone:
Chk1S345-R3F9
Isotype:
Rabbit IgG1k
Host:
Rabbit
Conjugation:
PE: Phycoerythrin
Application:
FC
Reconstitution and Storage:
2-8C
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser345 of human phospho Chk1
Purification:
Protein A+G
Datasheets/Manuals:
Printable datasheet for OAAQ00113
Target Post-Translational Modification:
Phospho-Ser345
Application Info:
For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
Target Reference:
1. Caprelli ML, et al. (2013) Cell Cycle, 12: 916-22.2. Capasso H, et al. (2002) J. Cell Sci. 115: 4555-64.3. Carrassa L, et al. (2011) Cell Cycle 10: 2121-8.4. Chen MS, et al. (2003) Mol. Cell Biol. 23: 7488-97.5. Ciccia A, et al. Mol. Cell 40: 179-204.6. Cimprich CA, (2014) Oncogene 33: 3351-607. Cremona CA, et al. (2014) Oncogene 33: 3351-60.8. Niida H, et al. (2007) Mol. Cell Biol. 27: 2572-81.
Gene Symbol:
CHEK1
Official Gene Full Name:
checkpoint kinase 1
Alias Symbols:
CHK1
NCBI Gene Id:
1111
Protein Name:
serine/threonine-protein kinase Chk1
Description of Target:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Swissprot Id:
O14757
Protein Accession #:
NP_001107593.1
Nucleotide Accession #:
NM_001114121.2
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CHEK1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CHEK1.
品牌介绍
avivasysbioVytas P. Ambutas- 董事会主席Ambutas先生是一家多元化的工业控股公司National Material LP的总法律顾问,秘书兼法律和行政副总裁。Ambutas先生是Tang Industries,Inc.的总法律顾问,Tang Industries,Inc.是一家多元化控股公司,包括工业,制药,家具和房地产控股公司,并担任高强度碳素钢加工商Nacme Steel Processing,LLC的董事,以及Key Colony,Inc.,果汁产品的制造商和分销商。Ambutas先生从1980年至1992年曾从事私人执业。Ambutas先生拥有芝加哥洛约拉法学院的法学博士学位和西密歇根大学的学士学位。朱利安- 董事会成员朱利安·袁(Julian Yuan)是联合创始人兼董事会成员。袁先生还是英杰华生物科技公司的联合创始人和董事会成员。袁先生自1983年成立以来,一直担任Progressive Group Inc.(PGI)的总裁兼首席执行官。PGI是其中之一。台湾最大的医疗器械经销商。袁先生是一位企业家,在生物科学产品,医疗设备和仪器的管理和营销方面拥有22年的经验。袁先生于1979年在台湾中原大学获得化学学士学位。Patrick Liang- 董事会成员梁先生现任唐实业有限公司中国业务董事总经理兼唐投资集团(中国)有限公司总裁。之前,梁先生曾任中国材料有限公司总经理,SKD中国副总裁,以及Irvine Networks业务开发副总裁兼SCA咨询管理顾问。梁先生拥有芝加哥大学布斯商学院的工商管理硕士学位和双学位,并拥有西北大学的经济学学士学位和国际研究学士学位。