MCL1 Antibody (OAEC04260)

来自 : 发布时间：2025-04-26

货号：	OAEC04260
抗体英文名：	MCL1 Antibody (OAEC04260)
靶点：	MCL1
宿主：	Mouse
适应物种：	Human
克隆性：	否
保存条件：	Store at 4C, for long term storage, store at -20C.
形态：	Purified antibody in PBS containing 0.03% sodium azide
亚型：	IgG1
免疫原：	Purified recombinant fragment of human MCL-1 expressed in EColi
规格：	100 ug/100 ul

NCBI Gene Id: 4170Swissprot Id: Q07820Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lym phocytes undergoing apoptosis following treatm ent with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expres sion of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSm yc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatm ent with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lys ate. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAEC04260

HepG2 cells

Confocal immunofluorescence analysis of HepG2 cells using MCL1 mouse mAb (green). Red. Actin filaments have been labeled with DY-554 phalloidin. Blue. DRAQ5 fluorescent DNA dye.

Human lymphnode tissues

Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using MCL1 mouse mAb with DAB staining.

Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate

Western blot analysis using MCL1 mouse mAb against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.

温馨提示：不可用于临床治疗。